CHEMBL478227


SMILES CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)[C@@H]2CCCC[C@@H]21
InChIKey PJRZQQXWGYRGCW-VQTJNVASSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 405.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.61 5.61 5.61 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.19 6.19 6.19 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database