CHEMBL514463


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCNC2CCCCC2)CN3c2ccccc2)c2ccccc21
InChIKey HQPWIOOFNUOPRR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 514.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.05 9.05 9.05 ChEMBL
δ OPRD Human Opioid A pKi 5.71 5.71 5.71 ChEMBL
κ OPRK Human Opioid A pKi 7.48 7.48 7.48 ChEMBL
μ OPRM Human Opioid A pKi 6.92 6.92 6.92 ChEMBL
δ OPRD Human Opioid A pKi 5.71 5.71 5.71 PDSP Ki database
NOP OPRX Human Opioid A pKi 9.05 9.05 9.05 PDSP Ki database
κ OPRK Human Opioid A pKi 7.48 7.48 7.48 PDSP Ki database
μ OPRM Human Opioid A pKi 6.92 6.92 6.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database