CHEMBL4784373


SMILES CC(=O)Nc1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)cc1
InChIKey TVTNBOZUNDIPJR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.67 5.67 5.67 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.79 7.79 7.79 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.46 8.46 8.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database