CHEMBL5173456


SMILES CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc1ccc(O)cc1
InChIKey NPOKHPMWBDEANH-MFMYLMPHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 569.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.25 7.25 7.25 ChEMBL
μ OPRM Human Opioid A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 7.37 7.37 7.37 ChEMBL
δ OPRD Mouse Opioid A pIC50 7.3 7.3 7.3 ChEMBL
δ OPRD Human Opioid A pEC50 6.18 6.18 6.18 ChEMBL
μ OPRM Human Opioid A pEC50 5.14 5.14 5.14 ChEMBL