CHEMBL514489


SMILES CC(C)NCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey DBUJJGVEYVDIRQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 474.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.85 8.85 8.85 ChEMBL
δ OPRD Human Opioid A pKi 5.3 5.3 5.3 ChEMBL
κ OPRK Human Opioid A pKi 7.17 7.17 7.17 ChEMBL
μ OPRM Human Opioid A pKi 7.16 7.16 7.16 ChEMBL
δ OPRD Human Opioid A pKi 5.3 5.3 5.3 PDSP Ki database
κ OPRK Human Opioid A pKi 7.17 7.17 7.17 PDSP Ki database
μ OPRM Human Opioid A pKi 7.16 7.16 7.16 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.85 8.85 8.85 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database