CHEMBL515142


SMILES CCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey YPOXRWBHPLIZDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.78 5.78 5.78 ChEMBL
κ OPRK Human Opioid A pKi 7.27 7.27 7.27 ChEMBL
μ OPRM Human Opioid A pKi 6.78 6.78 6.78 ChEMBL
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 PDSP Ki database
δ OPRD Human Opioid A pKi 5.78 5.78 5.78 PDSP Ki database
κ OPRK Human Opioid A pKi 7.27 7.27 7.27 PDSP Ki database
μ OPRM Human Opioid A pKi 6.78 6.78 6.78 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database