CHEMBL517028


SMILES CN1CCc2cc(-c3ccc(O)cc3)cc3c2[C@H]1Cc1ccc(O)c(O)c1-3
InChIKey IEYKUJATGFZIHM-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 359.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.75 8.75 8.75 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pIC50 8.43 8.43 8.43 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 8.07 8.07 8.07 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 8.07 8.07 8.07 ChEMBL