CHEMBL5190996


SMILES O=c1n(CC2CCC(CN3CCN(c4cccc(Cl)c4)CC3)CC2)nc2ccccn12
InChIKey OBWAPGCVMFPQBZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.34 5.34 5.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.25 6.25 6.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database