CHEMBL4847379


SMILES CCC(Oc1ccccc1)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey RGBWKRQKGURHQM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 328.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.7 4.7 4.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.3 6.49 7.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database