CHEMBL4854605


SMILES Clc1ccc(-c2n[nH]cc2N2CCCNCC2)cc1
InChIKey GQPFOKFRIDVKLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 276.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 4.61 5.12 5.63 ChEMBL