CHEMBL4858338


SMILES Clc1ccc(-c2n[nH]cc2N2CCNCC2)cc1
InChIKey RGVBFCBKZDWNNA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 262.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.63 7.63 7.64 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.05 6.05 6.05 ChEMBL