CHEMBL4858849


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(c1ccccc1)C(C)C
InChIKey VKBYQHKJRAFWOK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 388.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.1 5.1 5.1 ChEMBL
H2 HRH2 Human Histamine A pKi 7.45 7.45 7.45 ChEMBL
H1 HRH1 Human Histamine A pKi 4.61 4.61 4.61 ChEMBL
H3 HRH3 Human Histamine A pKi 4.72 4.72 4.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database