CHEMBL4863868


SMILES Cc1ccc(-c2n[nH]cc2N2CCCNCC2)cc1
InChIKey GEKVZXHRWKQTBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 256.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.37 5.37 5.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.76 5.76 5.76 ChEMBL