CHEMBL4870675


SMILES COc1cccc(-c2n[nH]cc2N2CCNCC2)c1
InChIKey PVXOGRBWNHUOLQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.06 5.06 5.07 ChEMBL