PROPOFOL


SMILES CC(C)c1cccc(C(C)C)c1O
InChIKey OLBCVFGFOZPWHH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 178.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.46 5.46 5.46 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 Drug Central
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.75 4.75 4.75 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 5.26 5.26 5.26 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 4.94 4.94 4.94 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.8 4.8 4.8 ChEMBL