CHEMBL4876799


SMILES CCCCCCNC(=O)/N=C(\N)NC1CCc2nc(N)sc2C1
InChIKey FZTHGRYFMPGYHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.78 4.78 4.78 ChEMBL
H2 HRH2 Human Histamine A pKi 5.95 5.95 5.95 ChEMBL
H1 HRH1 Human Histamine A pKi 5.71 5.71 5.71 ChEMBL
H3 HRH3 Human Histamine A pKi 5.82 5.82 5.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 6.83 6.83 6.83 ChEMBL