CHEMBL4877603


SMILES Clc1cccc(-c2n[nH]cc2N2CCCNCC2)c1
InChIKey QYUZYZBBJGTSFR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 276.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.18 8.18 8.19 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.16 6.16 6.16 ChEMBL