CHEMBL4878215


SMILES N/C(=N\C(=O)NCc1ccccc1)NC1CCc2nc(N)sc2C1
InChIKey KOIIIBWVKNCMBP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 344.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.52 4.52 4.52 ChEMBL
H2 HRH2 Human Histamine A pKi 6.29 6.29 6.29 ChEMBL
H1 HRH1 Human Histamine A pKi 5.92 5.92 5.92 ChEMBL
H3 HRH3 Human Histamine A pKi 5.48 5.48 5.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 5.36 6.02 6.67 ChEMBL