CHEMBL489408


SMILES COc1ccc(CCN2CCC(C(=O)c3cccc(OCCF)c3OC)CC2)cc1
InChIKey GWHHZSAHAOWCRM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.03 5.03 5.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database