CHEMBL493014


SMILES CC(C)(C)C#Cc1cccc(Cc2c[nH]cn2)c1
InChIKey KZWRVJZTROHTQZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 238.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 7.1 7.1 7.1 ChEMBL
H4 HRH4 Human Histamine A pKi 8.25 8.25 8.25 ChEMBL
H3 HRH3 Human Histamine A pKi 8.35 8.35 8.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 8.1 8.1 8.1 ChEMBL