CHEMBL495096


SMILES CC(Oc1ccccc1C1CCCC1)C1=NCCN1
InChIKey WIQCERUTOBWUOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 258.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.72 6.72 6.72 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.57 7.57 7.57 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.3 6.3 6.3 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 8.0 8.0 8.0 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.2 7.2 7.2 ChEMBL