CHEMBL495573


SMILES COc1cccc2cc3n(c12)CCN(CCCCN1CCn2c(cc4ccccc42)C1=O)C3
InChIKey GPANICKLGIVBML-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 442.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database