CHEMBL498150


SMILES CC(C)[C@H](NC(=O)C1CN(C)C1)c1cc(Cl)ccc1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
InChIKey SYIWIZYUJLMOJX-HRFSGMKKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 544.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.09 5.09 5.09 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.4 6.4 6.4 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.42 6.42 6.42 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.27 8.27 8.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 6.8 6.8 6.8 ChEMBL