CHEMBL541993


SMILES C[C@@H]1NC(NCC(F)F)=Nc2cccc(Cl)c21
InChIKey JDPGHZDOBUGUDU-LURJTMIESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 259.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.61 7.61 7.61 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.25 7.25 7.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database