CHEMBL5028997


SMILES CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NCCN1CCN(CCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey GMLQVLRORNVELR-ZPGRZCPFSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 8
Rotatable bonds 21
Molecular weight (Da) 830.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.65 6.65 6.65 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.51 8.51 8.51 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.76 6.76 6.76 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.67 9.67 9.67 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database