CHEMBL514074


SMILES COc1ccccc1N1CCN(CCCCSc2nc3ccccc3o2)CC1
InChIKey HZFUSQCPFRLRSJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 397.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.8 5.8 5.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.18 9.11 10.03 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.18 9.11 10.03 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.8 5.8 5.8 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database