CHEMBL576819


SMILES Cc1ccccc1COC1=NCCN1
InChIKey LGTDYALRCIBCMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 190.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.46 7.46 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.6 5.6 5.6 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.54 5.54 5.54 ChEMBL