CHEMBL5171734


SMILES Nc1nc(NCCNc2cccc(Cl)c2Cl)nc(NCCc2c[nH]c3ccccc23)n1
InChIKey VZXAKUVFURTEQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 9
Molecular weight (Da) 456.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.74 4.74 4.74 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.63 4.63 4.63 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database