CHEMBL517244


SMILES CN(CCCC12CCC(c3ccccc31)c1ccccc12)Cc1ccc(OCCCN2CCCCC2)cc1
InChIKey AQQFXOLTZFTABW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 11
Molecular weight (Da) 508.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
H1 HRH1 Human Histamine A pKi 7.4 7.4 7.4 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.69 6.69 6.69 ChEMBL
H3 HRH3 Human Histamine A pKi 9.45 9.45 9.45 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.83 6.83 6.83 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
H3 HRH3 Human Histamine A pKi 9.45 9.45 9.45 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 6.69 6.69 6.69 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 6.58 6.58 6.58 PDSP Ki database
H1 HRH1 Human Histamine A pKi 7.4 7.4 7.4 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.83 6.83 6.83 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database