CHEMBL5172673


SMILES O=c1n(CCCCCCN2CCN(c3cccc4cccnc34)CC2)nc2ccccn12
InChIKey XKFTZAKZMPILFS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database