ibotenic acid


SMILES OC(=O)C(c1o[nH]c(=O)c1)N
InChIKey IRJCBFDCFXCWGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 158.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pKi 4.37 4.37 4.37 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 4.77 4.77 4.77 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu6 GRM6 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.9 6.15 6.4 Guide to Pharmacology
mGlu4 GRM4 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pEC50 4.37 4.37 4.37 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.7 5.7 5.7 Guide to Pharmacology