CHEMBL517962


SMILES c1ccc(N2CCN(CCCSc3nc4ccccc4o3)CC2)nc1
InChIKey AHNRDNGNUMIWLX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database