CHEMBL5194614


SMILES Nc1nc(NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nc(NCCc2c[nH]c3ccccc23)n1
InChIKey XFPTZPCTBFZTJN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 553.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database