CHEMBL519609


SMILES CCN(CC)CCCOC(=O)N1c2ccccc2Sc2ccccc21
InChIKey FPUKGJMTLUQGFZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 356.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.57 5.57 5.57 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.92 6.92 6.92 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.22 6.22 6.22 ChEMBL
H2 HRH2 Human Histamine A pKi 5.85 5.85 5.85 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.68 7.68 7.68 ChEMBL
H1 HRH1 Human Histamine A pKi 6.37 6.37 6.37 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.77 6.77 6.77 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
H3 HRH3 Human Histamine A pKi 6.02 6.02 6.02 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.66 6.66 6.66 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.19 7.19 7.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database