CHEMBL5204088


SMILES O=S1(=O)N(CCCCCCN2CCN(c3cccc(Cl)c3)CC2)c2cccc3c2N1CCC3
InChIKey GGPXOELINLEIPA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database