FLUANISONE
SMILES | COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 |
InChIKey | IRYFCWPNDIUQOW-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 7 |
Molecular weight (Da) | 356.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D2 | DRD2 | Rat | Dopamine | A | pKi | 8.51 | 8.57 | 8.62 | ChEMBL |
5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 9.0 | 9.0 | 9.0 | ChEMBL |
5-HT2A | 5HT2A | Rat | 5-Hydroxytryptamine | A | pKi | 7.44 | 7.44 | 7.44 | PDSP Ki database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 6.1 | 6.1 | 6.1 | PDSP Ki database |
D2 | DRD2 | Bovine | Dopamine | A | pKi | 8.42 | 8.42 | 8.42 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |