CHEMBL60435


SMILES O=C(c1ccc(OCCCN2CCN(C(=O)C[C@H]3CCCN3)CC2)cc1)C1CC1
InChIKey ABEZUHIZVKNNOT-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 399.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.33 8.33 8.33 ChEMBL
H2 HRH2 Human Histamine A pKi 4.05 4.05 4.05 ChEMBL
H1 HRH1 Human Histamine A pKi 4.02 4.02 4.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database