CHEMBL598105
SMILES | CN1CCc2cc(Cl)c(O)cc2[C@H]2c3cccc(-c4cccc(C#N)c4)c3CC[C@@H]21 |
InChIKey | ALORGORVZSRMKI-AZGAKELHSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 1 |
Molecular weight (Da) | 414.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D5 | DRD5 | Human | Dopamine | A | pKi | 8.47 | 8.47 | 8.47 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 5.0 | 5.0 | 5.0 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 9.22 | 9.22 | 9.22 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.23 | 6.23 | 6.23 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |