CHEMBL5279730


SMILES O=[N+]([O-])C1=Cc2cc(Cl)ccc2OC1C(F)(F)F
InChIKey MZKIMVRXOFRAQO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 279.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y6 P2RY6 Mouse P2Y A pIC50 4.51 4.51 4.51 ChEMBL
P2Y6 P2RY6 Human P2Y A pIC50 5.75 5.75 5.75 ChEMBL