CHEMBL5289601


SMILES CN1/C(=C/C=C/C=C/C2=[N+](CCCCCC(=O)NCCCCCCCCN3CCC(COC(=O)Nc4ccc(F)cc4-c4ccc(F)c(Cl)c4)CC3)c3ccccc3C2(C)C)C(C)(C)c2ccccc21
InChIKey JGOIBENTSQHWDQ-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 22
Molecular weight (Da) 972.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.59 8.59 8.59 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.25 9.25 9.25 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.49 8.49 8.49 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.96 8.96 8.96 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.74 8.74 8.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database