TOLIPROLOL
| SMILES | Cc1cccc(OCC(O)CNC(C)C)c1 |
| InChIKey | NXQMNKUGGYNLBY-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 223.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| β2 | ADRB2 | Bovine | Adrenoceptors | A | pKd | 7.36 | 7.36 | 7.36 | ChEMBL |
| β1 | B0FL73 | Guinea pig | Adrenoceptors | A | pKd | 8.75 | 8.75 | 8.75 | ChEMBL |
| β2 | ADRB2 | Guinea pig | Adrenoceptors | A | pKd | 7.94 | 7.94 | 7.94 | ChEMBL |
| β1 | ADRB1 | Human | Adrenoceptors | A | pKd | 8.03 | 8.03 | 8.03 | Drug Central |
| β2 | ADRB2 | Human | Adrenoceptors | A | pKd | 8.05 | 8.05 | 8.05 | Drug Central |
| β2 | ADRB2 | Bovine | Adrenoceptors | A | pKd | 8.13 | 8.13 | 8.13 | Drug Central |
| β1 | B0FL73 | Guinea pig | Adrenoceptors | A | pKd | 8.06 | 8.06 | 8.06 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |