CHEMBL607689


SMILES Cn1c(CN2CCC(c3ccccc3F)CC2)nc2ccccc21
InChIKey AMADNKXMEDYTCS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 323.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.03 7.03 7.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 7.66 7.66 7.66 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.4 6.4 6.9 ChEMBL