CHEMBL550920


SMILES COc1ccc(N2CCN(Cc3c(C)nc4cc(C)ncn34)CC2)cc1
InChIKey FDBKWBKBMRKPJG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.57 4.57 4.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.89 4.96 5.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.0 5.02 5.04 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database