CHEMBL551199


SMILES Cn1c(N2CCCC2)nc2c(CN3CCN(c4ccccn4)CC3)c[nH]c2c1=O
InChIKey ILONWIHGXYVYRK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.55 8.55 8.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.51 6.51 6.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.7 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.7 6.82 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.51 6.51 6.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database