CHEMBL556288


SMILES Cn1c(N2CCCC2)nc2c(CN3CCN(c4ccccc4)CC3)c[nH]c2c1=O
InChIKey KTYLNGVSKMMZGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.6 6.6 6.6 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.42 8.42 8.42 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.41 6.58 6.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.41 6.58 6.74 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.48 6.48 6.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database