CHEMBL55654


SMILES Cc1ccc(Cl)cc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
InChIKey RURCUXSXKOFVNM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.43 9.43 9.43 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.58 7.58 7.58 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.72 6.72 6.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database