CHEMBL7143


SMILES COc1ccc2[nH]c(C)c(CCN(C)C)c2c1
InChIKey ACEHBQPPDDGCGZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 232.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 4.98 4.98 4.98 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.9 6.37 6.84 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.05 7.15 7.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database