CHEMBL558838


SMILES COc1ccccc1N1CCN(Cc2c(C)[nH]c3nc(N(C)C)ncc23)CC1
InChIKey ADAZZWTYEBRRHE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.17 5.17 5.17 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.19 8.19 8.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.21 5.21 5.21 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.56 5.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.56 5.59 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.21 5.21 5.21 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database