CHEMBL56118


SMILES N#Cc1c[nH]c(CN2CCN(c3ccccc3)CC2)c1
InChIKey IKBANCXZZJPIEB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 266.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.34 5.34 5.34 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.68 7.68 7.68 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.1 5.26 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.25 8.25 8.25 ChEMBL