CHEMBL75257


SMILES COc1c(C(C)(C)C)cc(C)c(Nc2ncc[nH]2)c1C
InChIKey AZADEQYOIWOMER-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 273.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 6.66 6.66 6.66 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.06 7.06 7.06 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.31 8.31 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pEC50 5.96 5.96 5.96 ChEMBL